• Skip to main content
  • Skip to header right navigation
  • Skip to site footer
  • Blog
  • Free Resources
RevistaLab

RevistaLab

  • About
    • Meet Revista
    • Partners
    • Press
    • Sponsorship
    • Contact Us
  • Events
  • Why Subscribe?
    • Subscriptions
    • Business Development
    • Underwriting & Due Diligence
    • Development
    • Asset Management
    • Leasing
  • SUBSCRIBER LOGIN
Home / Construction/Development / Life Science Real Estate in the Midwest

Life Science Real Estate in the Midwest

April 22, 2026 by Stephen Lindsey Topics: Construction/Development, Leasing/Property Management, Real Estate Financing/Capital Markets

When it comes to life science, the Midwest is often overshadowed by the core coastal hubs. However, the Midwest contains a strong ecosystem built on industrial infrastructure and solid talents pools. Revista is tracking over 56 million square feet of life science space in the Midwest region, with Chicago as the largest market by a large margin. Chicago contains 11.6 million square feet, with Minneapolis in second at 4.6. Most of the markets across the Midwest are anchored by user-owned pharmaceutical campuses with a handful of university and investor-owned lab buildings sprinkled in. To be specific, the overall ownership split is 68% life science/pharma, 16% investor/REIT, and 16% University/Health System.

The list on the right clearly shows the major presence of pharmaceutical companies like Abbot and Pfizer. Trammell Crow is the lone investor-owner to make the top list, and if we extended it further, we would see a couple of REITs with a 600k square feet each. About half of the investor-owned space is concentrated in Chicago and Minneapolis. In comparison to the rest of the Midwest, the Chicago market has struggled intensely with the supply/demand balance. Investor-owned space in Chicago suffers from higher vacancy rates than any of the core hubs across the US. Despite these struggles, the biomanufacturing ecosystem will continue to grow in the Midwest. Growth will create opportunities for real estate stakeholders, so make sure you are keeping an eye on more than just the coastal hubs.

Stephen Lindsey
Stephen Lindsey

Other Articles by Stephen Lindsey:

    • Life Science Manufacturing Campuses Popping up Across the US
    • Houston Life Science
    • Sublease Space More Prevalent in 2025

Previous Post:Some Markets are Recovering – Elsewhere Vacancy Continue to Climb

Sidebar

Topics

  • Construction/Development
  • Industry News
  • Leasing/Property Management
  • Mergers/Acquisitions
  • Policy/Legislation
  • Real Estate Financing/Capital Markets
  • Revista Best Practices
  • Revista News
  • Uncategorized

Recent Posts

  • Life Science Real Estate in the Midwest
  • Some Markets are Recovering – Elsewhere Vacancy Continue to Climb
  • Life Science Manufacturing Campuses Popping up Across the US
  • The Transaction Market for LSRE Off to a Healthy Start in 2026
  • Houston Life Science

Archives

Other Free Resources

Life Science Real Estate Industry Professionals

Search for and/or list your life science real estate services in Revista’s life science real estate directory.

Reports & White Papers

Download free reports & white papers on life science real estate.

Archives

  • April 2026
  • March 2026
  • February 2026
  • January 2026
  • December 2025
  • November 2025
  • October 2025
  • September 2025
  • August 2025
  • July 2025
  • June 2025
  • May 2025
  • April 2025
  • March 2025
  • February 2025
  • January 2025
  • December 2024
  • November 2024
  • October 2024
  • September 2024
  • August 2024
  • July 2024
  • June 2024
  • May 2024
  • April 2024
  • February 2024
  • November 2023
  • October 2023
  • August 2023
  • July 2023
  • June 2023
  • March 2023
  • October 2022
  • September 2022

Categories

  • Construction/Development
  • Industry News
  • Leasing/Property Management
  • Mergers/Acquisitions
  • Policy/Legislation
  • Real Estate Financing/Capital Markets
  • Revista Best Practices
  • Revista News
  • Uncategorized

Meta

  • Log in
  • Entries feed
  • Comments feed
  • WordPress.org

Ready to Schedule a Demo?

Get in Touch Now
  • Why Subscribe?
  • Events
  • The LAB Report
  • Add A Life Science Directory Listing
  • Contact Us
  • Sponsorship
  • About
  • Terms of Use
  • Press

SIGN UP FOR LAB REPORT NEWSLETTER

  • Twitter
  • Facebook
  • LinkedIn